Enhancing Data Sharing in Collaborative Research Projects with DASH Tom Ferrin Departments of Phamraceutical Chemistry and Biopharmaceutical Sciences University of California, San Francisco DASH (DAta SHaring) is an infrastructure for facilitating the construction, maintenance, and dissemination of shared data among researchers in small-to-mid sized collaborative projects. The DASH model is built around a "data network" comprised of data sources (database tables, filesystem files), and protocols (executable programs) that use those data sources as input and/or output. DASH monitors your data, detects changes as they occur, and responds to those changes in a timely manner. DASH can be used as a workflow management system for projects such as scientific databases or other large scale data-centric applications. While in traditional workflow management systems, a set of workflows are defined, then executed manually, DASH lets you define a complex web of workflows, and then decides which of these workflows need to be run in response to new or modified data in the system. While DASH runs on a single machine, it exposes a network API that enables DASH instances running on other machines to initiate workflows on the local instance, or receive notification of any changes to the local instances monitored data. The set of tools provided by DASH is both comprehensive enough to serve as the infrastructure for new collaborative projects, and flexible enough to be applied to existing ones.