|
Size: 262
Comment:
|
← Revision 5 as of 2009-11-16 20:23:59 ⇥
Size: 511
Comment:
|
| Deletions are marked like this. | Additions are marked like this. |
| Line 4: | Line 4: |
| While we are still developing and improving things, YES, definitely. We have successfully refined structures in EMAN2 to 6-8 A resolution from scratch, using EMAN2's new CTF correction scheme. |
YES, definitely. We have successfully refined structures in EMAN2 to 4-5 A resolution from scratch, using EMAN2's new CTF correction scheme. The new initial model generation method has sucessfully produced correct structures for ribosomes, GroEL, mm-cpn (closed), Ca++ release channel, and several other structures. While we naturally are continuing to make improvements, it is now reliable for single-model refinements to high resolution. |
Q: Can I use EMAN2 to run 3-D refinements yet ?
A: YES, definitely. We have successfully refined structures in EMAN2 to 4-5 A resolution from scratch, using EMAN2's new CTF correction scheme. The new initial model generation method has sucessfully produced correct structures for ribosomes, GroEL, mm-cpn (closed), Ca++ release channel, and several other structures. While we naturally are continuing to make improvements, it is now reliable for single-model refinements to high resolution.