'''Q: EMAN2 installed under Windows doesn't work properly. Any suggestions?''' Error details: {{{ C:\EMAN2>e2.py Traceback (most recent call last): File "C:\EMAN2\bin\e2.py", line 37, in import EMAN2 File "C:\EMAN2\lib\EMAN2.py", line 33, in from EMAN2_cppwrap import * File "C:\EMAN2\lib\EMAN2_cppwrap.py", line 33, in from libpyAligner2 import * !ImportError: No module named libpyAligner2 }}} '''A: ''' . You need change all libpy***.dll file to libpy***.pyd. Because ".dll is no longer supported as a filename extension for extension modules. .pyd is now the only filename extension that will searchfor". .