Rosetta

Thursday PM Practical

Rosetta is a library based object-oriented software suite which provides a robust system for predicting and designing protein structures, protein folding mechanisms, and protein-protein interactions.

For the tutorial, you could get the binaries of Rosetta for both Linux and Mac platform through the following links. Afterwards, please add the following two lines in your .bashrc file and do "source ~/.bashrc". Please adjust accordingly in your own computer.

export ROSETTA3_SRC=/home/eman/eman2011/rosetta/rosetta_binaries_linux export ROSETTA3_DB=/home/eman/eman2011/rosetta/rosetta_database

For installation of the standard release, the latest release of Rosetta, version 3.2, may be downloaded at http://www.rosettacommons.org/software. The software is free to academic users, who may get a license (and download link) by clicking on the appropriate link on the left side of the page. The user manual, containing more detailed installation and usage information, is available online at http://www.rosettacommons.org/manuals/archive/rosetta3.2_user_guide.

More details about the installation guide can be downloaded through Installation_Guide.pdf

You can download the tutorial data throughrosetta_tutorial_data.tar, and the tutorial documentation through Rosetta_Density_Tutorial.pdf